Gestational choriocarcinoma is a malignant trophoblastic tumor arising from any gestational event, even with a long latency period, generally in the reproductive female. It is associated with a high level of beta-human chorionic gonadotropin. Its primary site is usually the uterus but not all patients have a detectable lesion in this site. Regression of the primary tumor after it has metastasized is not uncommon, and one-third of cases manifest as complications of metastatic disease. In this report we present an uncommon case of gestational choriocarcinoma with lung, liver and jejunal metastases at the time of diagnosis without evidence of pelvic disease, in 34-year-old woman. The main points of interest of our case were the development of the ovarian hyperstimulation syndrome with massive multicystic ovarian enlargement induced by high level of beta-human chorionic gonadotropin and the bleeding of jejunal and liver metastases, due to the high vascularity of the tumor tissue, a condition known as "Choriocarcinoma Syndrome". We will focus on the radiological findings of metastases, bleeding complications and ovarian hyperstimulation syndrome.
Keywords: CE-CT, Contrast Enhancement Computed Tomography; Choriocarcinoma syndrome; FSH, Follicle Stimulating Hormone; Gestational choriocarcinoma; HU, Hounsfield Unit; Hemorrhagic metastases; Hypervascular metastases; LH, Luteinizing Hormone; MIP, Maximum Intensity Projection; MPR, Multiplanar Reconstruction; MRI, Magnetic Resonance Imaging; OHSS, Ovarian Hyperstimulation Syndrome; Ovarian hyperstimulation syndrome; TSH, Thyroid Stimulating Hormone; US, Ultrasonography; b-hCG, Beta Human Chorionic Gonadotropin.
© 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington.