Paediatric otogenic cerebral venous sinus thrombosis: a multidisciplinary approach

J Laryngol Otol. 2022 Jan;136(1):3-7. doi: 10.1017/S0022215121003145. Epub 2021 Oct 26.

Abstract

Background: Paediatric otogenic cerebral venous sinus thrombosis is a rare, heterogeneous and life-threatening condition, with possible otological, neurological and ophthalmological sequelae. Its course and outcomes can be widely variable. The publications available often consider individual aspects of paediatric otogenic cerebral venous sinus thrombosis management. The condition itself and the nature of the currently available guidance can lead to uncertainties when holistically managing patients with paediatric otogenic cerebral venous sinus thrombosis.

Objectives: Clear recommendations for the comprehensive assessment and management of paediatric otogenic cerebral venous sinus thrombosis are presented, along with the literature review upon which they are based. Its clinical and radiological assessment are discussed.

Conclusion: A multidisciplinary approach to assessment and management is recommended, inclusive of infectious diseases, ENT surgery, neurology, ophthalmology and haematology. On balance, anticoagulation is recommended for three months. Follow-up imaging is not recommended in the absence of clinical concern. Follow up by ENT surgery, neurology and ophthalmology departments is recommended.

Keywords: Hematology; Mastoiditis; Neurology; Ophthalmology; Otitis Media; Otolaryngology; Pediatrics; Radiology; Thrombosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child, Preschool
  • Female
  • Humans
  • Mastoiditis / complications*
  • Mastoiditis / diagnosis
  • Mastoiditis / therapy
  • Sinus Thrombosis, Intracranial / diagnosis
  • Sinus Thrombosis, Intracranial / etiology*
  • Sinus Thrombosis, Intracranial / therapy