Secondary Cases of Delta Variant Coronavirus Disease 2019 Among Vaccinated Healthcare Workers With Breakthrough Infections is Rare

Sarah E Waldman; Tara Buehring; Daniel J Escobar; Shruti K Gohil; Ralph Gonzales; Susan S Huang; Keith Olenslager; Kavitha K Prabaker; Tessa Sandoval; Jennifer Yim; Deborah S Yokoe; Stuart H Cohen

doi:10.1093/cid/ciab916

Secondary Cases of Delta Variant Coronavirus Disease 2019 Among Vaccinated Healthcare Workers With Breakthrough Infections is Rare

Clin Infect Dis. 2022 Aug 24;75(1):e895-e897. doi: 10.1093/cid/ciab916.

Authors

Affiliations

¹ Division of Infectious Diseases, Department of Medicine, University of California Davis, Sacramento, California, USA.
² Clinical Epidemiology and Infection Prevention, University of California Los Angeles, Los Angeles Health, Los Angeles, California, USA.
³ Division of Infectious Disease, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
⁴ Division of Infectious Diseases and Health Policy Research Institute, University of California Irvine School of Medicine, Irvine, California, USA.
⁵ Department of Medicine and Clinical Innovation Center, University of California San Francisco, San Francisco, California, USA.
⁶ Epidemiology & Infection Prevention Program, University of California, Irvine Health, Irvine, California, USA.
⁷ Division of Infectious Diseases, Department of Medicine, University of California Los Angeles, Los Angeles, California, USA.

Abstract

In a retrospective, cohort study at 4 medical centers with high coronavirus disease 2019 vaccination rates, we evaluated breakthrough severe acute respiratory syndrome coronavirus 2 Delta variant infections in vaccinated healthcare workers. Few work-related secondary cases were identified. Breakthrough cases were largely due to unmasked social activities outside of work.

Keywords: B.1.617.2; COVID-19; breakthrough; healthcare worker; vaccination.

Publication types

Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, P.H.S.

MeSH terms

COVID-19* / prevention & control
Cohort Studies
Health Personnel
Humans
Retrospective Studies
SARS-CoV-2
Vaccination

Supplementary concepts

SARS-CoV-2 variants

Grants and funding

U54 CK000484/CK/NCEZID CDC HHS/United States