1 Section of Psychiatry, Department of Neuroscience, Ophthalmology, Genetics and Infant-Maternal Science, University of Genoa, Genoa, Italy, and Department of Psychological Medicine, Institute of Psychiatry, King's College London, London, UK; Section of Psychiatry, Department of Neuroscience, Ophthalmology, Genetics and Infant-Maternal Science, University of Genoa, Italy; Department of Medical and Surgical Sciences, University of Bologna; Cardiology Unit, Ramazzini Hospital, Carpi; Department of Geriatrics, Nuovo Ospedale Civile S. Agostino Estense, Modena and Reggio Emilia University, Modena; Department of Biomedical and Neuromotor Sciences, University of Bologna; Department of Biomolecular Sciences, Service of Biostatistics, University of Urbino; primary care physicians, Bologna; Department of Movement and Neurological Sciences, University of Verona; Unit of Internal Medicine, Geriatrics and Nephrology, S. Orsola Malpighi Hospital, Bologna; Consultation Liaison Psychiatry Service, Department of Mental Health, Bologna; Department of Geriatrics, Nuovo Ospedale Civile S. Agostino Estense, Modena and Reggio Emilia University, Modena, Italy; Department of Psychiatry, Weill Cornell Medical College, New York, USA; Consultation Liaison Psychiatry Service, Department of Mental Health, Bologna, Italy; the Safety and Efficacy of Exercise for Depression in Seniors (SEEDS) Study Group.