Vitamin D Status and Physical Activity during Wintertime in Forensic Inpatients-A Randomized Clinical Trial

Nutrients. 2021 Oct 5;13(10):3510. doi: 10.3390/nu13103510.

Abstract

This study aimed to gain deeper knowledge about the relationship between vitamin D and physical activity in a sample of forensic inpatients. Sixty-seven male forensic inpatients participated. Participants were randomly assigned into an Intervention group (vitamin D) or a Control group (placebo). The Physical Activity-Rating (PA-R) questionnaire was used to measure physical activity from January to May. Vitamin D status was measured as 25-hydroxy vitamin D (25-OHD) pre- and post-intervention. The results revealed that vitamin D status at post-test was positively correlated with physical activity, but there was no effect of vitamin D supplementation looking at the two randomized groups. However, controlling for body mass index (BMI), the results showed an effect of BMI and a main effect of groups with a higher level of physical activity in the Intervention group. No interaction effects were found. Participants were also assigned into High and Low vitamin D groups based on the vitamin D status at post-test; i.e., the upper (75.1 nmol/L) and lower quartile (46.7 nmol/L). T-tests revealed that participants with a vitamin D status above 75 nmol/L showed significantly higher levels of physical activity than participants with a vitamin D status below 46.7 nmol/L. Thus, a vitamin D status above 75 nmol/L seems to be an optimal level.

Keywords: physical activity; randomized control trial; supplements; vitamin D status; winter.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Body Mass Index
  • Dietary Supplements*
  • Double-Blind Method
  • Exercise / physiology*
  • Humans
  • Inpatients
  • Male
  • Middle Aged
  • Nutritional Status / drug effects*
  • Prisoners
  • Seasons
  • Treatment Outcome
  • Vitamin D / administration & dosage*
  • Vitamin D / analogs & derivatives*
  • Vitamin D / blood
  • Vitamin D Deficiency / blood
  • Vitamin D Deficiency / therapy
  • Vitamins / administration & dosage*

Substances

  • Vitamins
  • Vitamin D
  • 25-hydroxyvitamin D