Can the Nasal Cavity Help Tackle COVID-19?

Bissera Pilicheva; Radka Boyuklieva

doi:10.3390/pharmaceutics13101612

Can the Nasal Cavity Help Tackle COVID-19?

Pharmaceutics. 2021 Oct 3;13(10):1612. doi: 10.3390/pharmaceutics13101612.

Authors

Bissera Pilicheva^{1

2}, Radka Boyuklieva¹

Affiliations

¹ Department of Pharmaceutical Sciences, Faculty of Pharmacy, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
² Research Institute at Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.

Abstract

Despite the progress made in the fight against the COVID-19 pandemic, it still poses dramatic challenges for scientists around the world. Various approaches are applied, including repurposed medications and alternative routes for administration. Several vaccines have been approved, and many more are under clinical and preclinical investigation. This review aims to systemize the available information and to outline the key therapeutic strategies for COVID-19, based on the nasal route of administration.

Keywords: COVID-19; SARS-CoV-2; intranasal delivery; nasal cavity; nasal vaccine.

Publication types

Review