The porin AaxA protein model from Chlamydia pneumonia

Jayaraman Selvaraj; Srinivasan Perumal; Josephine Rex; Surapaneni Krishna Mohan; Sumetha Suga Deiva Suga; Umapathy Vidhya Rekh; Veeraraghavan Vishnupriya; Periyasamy Vijayalakshmi; Rajagopal Ponnulakshmi

doi:10.6026/97320630016786

The porin AaxA protein model from Chlamydia pneumonia

Bioinformation. 2020 Oct 31;16(10):786-788. doi: 10.6026/97320630016786. eCollection 2020.

Authors

Jayaraman Selvaraj¹, Srinivasan Perumal², Josephine Rex³, Surapaneni Krishna Mohan³, Sumetha Suga Deiva Suga⁴, Umapathy Vidhya Rekh⁵, Veeraraghavan Vishnupriya¹, Periyasamy Vijayalakshmi, Rajagopal Ponnulakshmi

Affiliations

¹ Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India.
² Department of Biochemistry, School of Life Sciences, Vels Institute of Science Technology and Advanced Studies (VISTAS), Pallavaram, Chennai- 600 117, India.
³ Department of Biochemistry, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123, India.
⁴ PG & Research Department of Biotechnology & Bioinformatics, Holy Cross College (Autonomous), Trichy- 620002, Tamil Nadu, India.
⁵ Central Research Laboratory, Meenakshi Academy of Higher Education and Research, Chennai-600 078, India.

Abstract

Chlamydophila pneumoniae is an intracellular pathogen accountable for various acute respiratory infections. C. pneumoniae has a gene cluster which encodes a putative outer membrane porin (aaxA), arginine decarboxylase (CPn1032 or aaxB) and a putative cytoplasmic membrane transporter (CPn1031 or aaxC). Therefore, it is of interest to document a molecular protein model of porin AaxA from Chlamydia pneumonia to gain structure to functional insight on the protein.

Keywords: AaxA; Chlamydophila pneumonia; homology modelling.