Translating the advanced glycation end products (AGEs) knowledge into real-world nutrition strategies

Eur J Clin Nutr. 2022 Jul;76(7):922-928. doi: 10.1038/s41430-021-01028-8. Epub 2021 Oct 21.

Abstract

Advanced glycation end products (AGEs) are glycated proteins or lipids derived from complex metabolic pathways involved in the pathophysiology of various diseases, especially diabetes and diabetes-related complications. These compounds are omnipresent in human life, with both endogenous and exogenous sources. Despite the well-elucidated disease mechanisms, little is known about the AGEs/nutrition nexus in the circles of clinical practice recommendations. This review seeks to translate the accumulated knowledge about the biochemistry and pathophysiology of AGEs into a nutritional intervention based on real-world prescriptions.

Publication types

  • Review

MeSH terms

  • Diabetes Complications*
  • Diabetes Mellitus*
  • Glycation End Products, Advanced
  • Humans

Substances

  • Glycation End Products, Advanced