Year-Long Trend in Glycated Hemoglobin Levels in Patients with Type 2 Diabetes during the COVID-19 Pandemic

Endocrinol Metab (Seoul). 2021 Oct;36(5):1142-1146. doi: 10.3803/EnM.2021.1154. Epub 2021 Oct 21.

Abstract

It has been suggested that the coronavirus disease 2019 (COVID-19) pandemic has had a negative impact on glycemic control in patients with type 2 diabetes mellitus (T2DM). However, no study has examined yearly trends in glycated hemoglobin (HbA1c) levels after the start of the COVID-19 outbreak. Here, we performed a retrospective analysis of HbA1c concentrations during the early period of the COVID-19 outbreak (COVID-19 cohort) and then compared the yearly trend in the mean HbA1c level, along with fluctuations in HbA1c levels, with those during previous years (non-COVID-19 cohorts). We observed that the mean HbA1c level in patients with T2DM increased during the first 6 months of the COVID-19 outbreak. After 6 months, HbA1c levels in the COVID-19 cohort returned to levels seen in the non-COVID-19 cohorts. The data suggest that vulnerable patients with T2DM should be monitored closely during the early period of a pandemic to ensure they receive appropriate care.

Keywords: COVID-19; Diabetes mellitus; Glycated hemoglobin A; Physical distancing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Glucose / analysis
  • COVID-19 / diagnosis
  • COVID-19 / epidemiology*
  • COVID-19 / virology
  • Case-Control Studies
  • Diabetes Mellitus, Type 2 / blood*
  • Diabetes Mellitus, Type 2 / epidemiology
  • Disease Outbreaks / statistics & numerical data
  • Female
  • Glycated Hemoglobin / analysis*
  • Glycemic Control / trends*
  • Humans
  • Male
  • Retrospective Studies
  • SARS-CoV-2 / genetics
  • Time Factors

Substances

  • Blood Glucose
  • Glycated Hemoglobin A