Caution in underrepresentation of older adults in clinical trials on COVID-19 vaccines

Yamin Chen; Zhifan Li; Ya Gao; Jinhui Tian

doi:10.1016/j.arr.2021.101486

Caution in underrepresentation of older adults in clinical trials on COVID-19 vaccines

Ageing Res Rev. 2021 Dec:72:101486. doi: 10.1016/j.arr.2021.101486. Epub 2021 Oct 18.

Authors

Yamin Chen¹, Zhifan Li², Ya Gao¹, Jinhui Tian³

Affiliations

¹ Evidence-Based Medicine Centre, School of Basic Medical Sciences, Lanzhou University, No.199, Donggang West Road, Lanzhou City 730000, Gansu Province, China.
² The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China; First Hospital of Lanzhou University, Lanzhou 730000, China.
³ Evidence-Based Medicine Centre, School of Basic Medical Sciences, Lanzhou University, No.199, Donggang West Road, Lanzhou City 730000, Gansu Province, China; Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China. Electronic address: tianjh@lzu.edu.cn.

Abstract

We read with great interest the article "Underrepresentation of older adults in clinical trials on COVID-19 vaccines: A systematic review" written by Nicola Veronese et al. This important work demonstrated that medications and vaccines commonly used in older adults have not been adequately evaluated. Concerning this systematic review, we shall like to mention some certain points deserved to be attended by the authors.

Keywords: COVID-19; Letter to the editor; Older adults; Vaccination.

Publication types

Letter
Comment

MeSH terms

Aged
COVID-19 Vaccines
COVID-19*
Humans
SARS-CoV-2
Vaccines* / adverse effects

Substances

COVID-19 Vaccines
Vaccines