Pathologically stiff erythrocytes impede contraction of blood clots: Reply to comment
J Thromb Haemost
.
2021 Nov;19(11):2894-2895.
doi: 10.1111/jth.15511.
Authors
Valerie Tutwiler
1
2
,
Rustem I Litvinov
1
3
,
Anna Protopopova
1
,
Chandrasekaran Nagaswami
1
,
Carlos Villa
4
,
Eric Woods
5
,
Osheiza Abdulmalik
6
,
Don L Siegel
4
,
J Eric Russell
7
,
Vladimir R Muzykantov
8
,
Wilbur A Lam
9
,
David R Myers
9
,
John W Weisel
1
Affiliations
1
Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
2
Department of Biomedical Engineering, Rutgers - The State University of New Jersey, Piscataway, New Jersey, USA.
3
Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
4
Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
5
Max-Planck-Institut für Eisenforschung GmbH Düsseldorf, Düsseldorf, Germany.
6
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
7
Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
8
Department of Pharmacology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
9
The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA.
PMID:
34668295
PMCID:
PMC10031937
DOI:
10.1111/jth.15511
No abstract available
Keywords:
blood clotting; clot contraction; erythrocytes; sickle cell disease; thrombosis.
Publication types
Letter
Comment
MeSH terms
Erythrocytes
Humans
Thrombosis*
Grants and funding
R01 HL159256/HL/NHLBI NIH HHS/United States
T32 HL007775/HL/NHLBI NIH HHS/United States