Acquired Dermal Macular Hyperpigmentation: An Update

Indian Dermatol Online J. 2021 Aug 2;12(5):663-673. doi: 10.4103/idoj.IDOJ_881_20. eCollection 2021 Sep-Oct.

Abstract

Acquired dermal macular hyperpigmentation (ADMH) is an umbrella term that includes disorders clinically characterized by small and large pigmented macules/patches and histopathologically showing an evidence of current or resolved interface dermatitis with pigment incontinence, without clinically significant prior inflammatory phase. The term intends to include diseases previously described in the literature as lichen planus pigmentosus, Riehl's melanosis/pigmented cosmetic dermatitis and ashy dermatosis/erythema dyschromicum perstans. The nomenclature and origin of these disorders have always been a matter of discussion. These disorders share many clinicopathological similarities, are difficult to treat and adversely affect the quality of life. Recent consensus points towards the need for a unifying term to facilitate research and therapeutic trials. This article aims to provide a comprehensive review of the recent advances in ADMH.

Keywords: Acquired dermal macular hyperpigmentation; Reihl's melanosis; ashy dermatosis; erythema dyschromia perstans; lichen planus pigmentosus; pigmented cosmetic dermatitis.

Publication types

  • Review