Isolation and identification of marine microbial products

Sahar Saleh Mohamed; Sayeda Abdelrazek Abdelhamid; Radwa Hassaan Ali

doi:10.1186/s43141-021-00259-3

Isolation and identification of marine microbial products

J Genet Eng Biotechnol. 2021 Oct 19;19(1):162. doi: 10.1186/s43141-021-00259-3.

Authors

Sahar Saleh Mohamed¹, Sayeda Abdelrazek Abdelhamid², Radwa Hassaan Ali³

Affiliations

¹ Microbial Biotechnology Department, Genetic Engineering Division, National Research Centre, Cairo, Egypt.
² Microbial Biotechnology Department, Genetic Engineering Division, National Research Centre, Cairo, Egypt. sayeda.abdelrazek@yahoo.com.
³ Masoud Hospital, Cairo, Egypt.

Abstract

Background: The ocean is one of the world's most important sources of bioactive chemicals in the marine environment. Microbiologists, ecologists, agronomists, taxonomists, and evolutionary biologists have been increasingly interested in marine microbial natural products (MMNPs) in recent decades.

Main body: Diverse marine bacteria appear to get the ability to manufacture an astounding diversity of MMNPs with a wide range of biological actions, including anti-tumor, antimicrobial, and anti-cardiovascular agents according to numerous studies.

Short conclusions: Innovative isolation and culture methodologies, tactics for identifying novel MMNPs via routine screens, metagenomics, genomics, combinatorial biosynthesis, and synthetic biology are all discussed in this review. There is also a discussion of potential issues and future directions for studying MMNPs.

Keywords: Bioactive compounds; MMNPs; Marine microbial; Natural products.

Publication types

Review