Abstract
In this study, we introduced four "claw-like" units of dipicolylamine (DPA) to a tetraphenylethylene (TPE)-based organic molecular cage (DPA-TPE-Cage). Coordinated with Zn2+ ions, the obtained ZnDPA-TPE-Cage exhibited aggregation induced emission (AIE) effects and oxidase-like properties, which endowed it with the ability to selectively image and kill Gram-positive bacteria S. aureus efficiently.
MeSH terms
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Amines / chemistry
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Amines / pharmacology
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Amines / radiation effects
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / pharmacology*
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Anti-Bacterial Agents / radiation effects
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Catalysis / radiation effects
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Cell Membrane / drug effects
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Fluorescent Dyes / chemistry
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Fluorescent Dyes / pharmacology*
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Fluorescent Dyes / radiation effects
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Light
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Microbial Sensitivity Tests
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Nanoparticles / chemistry*
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Nanoparticles / radiation effects
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Picolinic Acids / chemistry
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Picolinic Acids / pharmacology
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Picolinic Acids / radiation effects
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Reactive Oxygen Species / metabolism
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Staphylococcus aureus / drug effects
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Stilbenes / chemistry
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Stilbenes / pharmacology
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Stilbenes / radiation effects
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Zinc / chemistry
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Zinc / pharmacology
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Zinc / radiation effects
Substances
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2,2'-dipicolylamine
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Amines
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Anti-Bacterial Agents
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Fluorescent Dyes
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Picolinic Acids
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Reactive Oxygen Species
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Stilbenes
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Zinc