Effects of chronic betaine supplementation on performance in professional young soccer players during a competitive season: a double blind, randomized, placebo-controlled trial

J Int Soc Sports Nutr. 2021 Oct 18;18(1):67. doi: 10.1186/s12970-021-00464-y.

Abstract

Objective: Various nutritional strategies are adopted for athletes to maintain and to improve performance during the competition season. Betaine may enhance performance during a competitive season by increasing the testosterone to cortisol ratio and reducing systemic inflammation. The aim of this study was to investigate the effect of betaine supplementation on the bio-motor abilities in young professional soccer players.

Methods: Twenty-nine young professional soccer players (age, 15.5±0.3 years) were matched by position and randomly assigned to one of two groups for 14 weeks: betaine (BG, 2 g/day; n=14) or placebo (PG n=15). Diet was standardized by a nutritionist, and measures of muscular power (countermovement jump: CMJ), change of direction: modified 5-0-5), acceleration (10 m sprint), sprint performance (30 m sprint time: SpT), muscular strength (leg press and bench press one repetition maximum: 1-RM), repeated sprint ability (running-based anaerobic sprint test: RAST), and aerobic capacity (30-15 intermittent fitness test) were assessed in the pre (P1), mid (P2) and post (P3) season over the course of 5 days. All subjects participated in one soccer match and five training sessions per week.

Results: Significant (p < 0.05) group x time interactions were found for maximal oxygen uptake (VO2max), anaerobic peak power, and muscular strength favoring BG at P2 and P3 compared to P1. There were meaningful (p < 0.05) group x time interactions for CMJ, SpT, and peak power during the RAST that favored the BG.

Conclusions: 14-week of betaine supplementation increased predicted 1-RM, VO2max, and repeated sprint ability performance in youth professional soccer players. Betaine supplementation seems to be a useful nutritional strategy to improve and to maintain performance during a competitive soccer season.

Keywords: 1-RM; Anaerobic peak power; CMJ; Football; RSA; VO2max; Young sports.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Acceleration
  • Adolescent
  • Athletic Performance / physiology*
  • Betaine / administration & dosage*
  • Competitive Behavior
  • Dietary Supplements*
  • Double-Blind Method
  • Exercise Test
  • Humans
  • Hydrocortisone / blood
  • Male
  • Muscle Strength
  • Oxygen Consumption
  • Performance-Enhancing Substances / administration & dosage*
  • Physical Conditioning, Human
  • Running / physiology
  • Soccer / physiology*
  • Testosterone / blood

Substances

  • Performance-Enhancing Substances
  • Betaine
  • Testosterone
  • Hydrocortisone