Degradation of chitosan in solution by gamma irradiation in the presence of hydrogen peroxide

Nguyen Quoc Hien; Dang Van Phu; Nguyen Ngoc Duy; Nguyen Thi Kim Lan

doi:10.1016/j.carbpol.2011.08.018

Degradation of chitosan in solution by gamma irradiation in the presence of hydrogen peroxide

Carbohydr Polym. 2012 Jan 4;87(1):935-938. doi: 10.1016/j.carbpol.2011.08.018. Epub 2011 Aug 17.

Authors

Nguyen Quoc Hien¹, Dang Van Phu², Nguyen Ngoc Duy², Nguyen Thi Kim Lan²

Affiliations

¹ Research and Development Center for Radiation Technology, Vietnam Atomic Energy Institute, 202A, Street 11, Linh Xuan Ward, Thu Duc District, Ho Chi Minh City, Viet Nam. Electronic address: hien7240238@yahoo.com.
² Research and Development Center for Radiation Technology, Vietnam Atomic Energy Institute, 202A, Street 11, Linh Xuan Ward, Thu Duc District, Ho Chi Minh City, Viet Nam.

PMID: 34663058
DOI: 10.1016/j.carbpol.2011.08.018

Abstract

Chitosan from squid pens with deacetylation degree (DD) of 70% and average molecular weight (M_w0) 90.5×10³ in dilute lactic acid solution containing H₂O₂ (1%) was effectively degraded by irradiation with gamma ⁶⁰Co radiation (1.33kGy/h) at doses in the range 4-16kGy. Based on the results of M_w measured by gel permeation chromatography (GPC), it was concluded that there was particularly strong synergy between H₂O₂ and radiation for degradation at the lower radiation doses studied. Radiation scission yields (Gs) were found out to be 2.2μmol/J and 0.2μmol/J for 5% chitosan with and without 1% H₂O₂, respectively. The DD of degraded chitosan measured from IR spectra was almost unchanged by the treatment.

Keywords: Chitosan; Degradation; Hydrogen peroxide; γ-Ray.