How did we reform our out of control massive transfusion protocol program?

Transfusion. 2021 Nov;61(11):3066-3074. doi: 10.1111/trf.16706. Epub 2021 Oct 18.

Abstract

Background: The massive transfusion protocol (MTP) is designed to quickly provide blood products at a fixed ratio for the exsanguinating patient. At our academic medical center, the frequency of MTP activation increased over 10-fold between 2008 and 2015, putting inordinate stress on our transfusion service.

Study design and methods: Gathering a large number of relevant stakeholders, we performed a multidisciplinary root cause analysis (RCA) in response to the acute clinical need to reform our MTP.

Results: Through the RCA, we identified four principal opportunities for improvement (OFI) associated with our MTP: education, stewardship, process improvement, and communication. Through the deployment of new approaches to each of these OFI, we reduced MTP activations, blood product waste, and transfusion service technologist stress.

Conclusion: The MTP is amenable to improvement, and, although time intensive, the RCA process yields significant favorable effects: improving communication with colleagues, reducing stress within the transfusion service, and improving resource utilization. Activation of the MTP at our institution is now more aligned with its primary purpose: rapidly providing large quantities of blood products to exsanguinating patients.

Keywords: management; massive transfusion protocols; quality; transfusion practice.

MeSH terms

  • Academic Medical Centers
  • Blood Transfusion* / methods
  • Health Facilities
  • Humans
  • Retrospective Studies
  • Trauma Centers
  • Wounds and Injuries*