Pharmacological effects of Picrasma quassioides (D. Don) Benn for inflammation, cancer and neuroprotection (Review)

Exp Ther Med. 2021 Dec;22(6):1357. doi: 10.3892/etm.2021.10792. Epub 2021 Sep 24.

Abstract

Picrasma quassioides (D. Don) Benn is an Asian shrub with a considerable history of traditional medicinal use. P. quassioides and its extracts exhibit good therapeutic properties against several diseases, including anti-inflammatory, antibacterial and anticancer effects. However, the composition of compounds contained in P. quassioides is complex; although various studies have examined mixtures or individual compounds extracted from it, studies on the application of P. quassioides extracts remain limited. In the present review, the structures and functions of the compounds identified from P. quassioides and their utility in anti-inflammatory, anticancer and neuroprotectant therapies was discussed. The present review provided up-to-date information on pharmacological activities and clinical applications for P. quassioides extracts.

Keywords: Picrasma quassioides (D. Don) Benn; alkaloid; bis-β-carboline; carthinone; quassinoids; triterpenoids; β-carboline.

Publication types

  • Review

Grants and funding

Funding: The present study was supported by the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education (grant no. 2020R1I1A2052417) and The Korean Research Institute of Bioscience and Biotechnology Research Information System (grant no. RBM0112112).