Arterial hypertension of infrequent cause

A Rosales-Castillo; A Bustos-Merlo

doi:10.1016/j.hipert.2021.09.002

Arterial hypertension of infrequent cause

Hipertens Riesgo Vasc. 2022 Apr-Jun;39(2):92-94. doi: 10.1016/j.hipert.2021.09.002. Epub 2021 Oct 13.

Authors

A Rosales-Castillo¹, A Bustos-Merlo²

Affiliations

¹ Servicio de Medicina Interna, Hospital Universitario Virgen de las Nieves, Granada, Spain. Electronic address: anrocas90@hotmail.com.
² Servicio de Medicina Interna, Hospital Universitario Virgen de las Nieves, Granada, Spain.

PMID: 34656459
DOI: 10.1016/j.hipert.2021.09.002

Abstract

Arterial hypertension is generally classified as primary or essential (90%), and secondary (10%). Infrequent causes of the latter include Cushing's syndrome, classified as ACTH-dependent and independent. A small percentage of ACTH-independent cases are due to ectopic ACTH secretion, generally due to neoplasia, and can present as arterial hypertension and hyperglycaemia that are refractory to pharmacological measures, metabolic alkalosis and hypokalaemia that are difficult to control, but which help guide the initial diagnosis. We present two clinical cases with a diagnosis of ectopic ACTH secretion secondary to small cell lung carcinoma, in which one of the debut manifestations was unknown, difficult to control arterial hypertension.

Keywords: ACTH; Hipertensión; Hipopotasemia; Hypertension; Hypokalaemia; Neoplasia.

Publication types

Case Reports

MeSH terms

ACTH Syndrome, Ectopic* / complications
ACTH Syndrome, Ectopic* / diagnosis
Adrenocorticotropic Hormone / metabolism
Cushing Syndrome* / diagnosis
Cushing Syndrome* / etiology
Humans
Hypertension* / complications
Hypokalemia* / etiology

Substances

Adrenocorticotropic Hormone