3q21 deletion affects GATA2 and is associated with myelodysplastic syndrome

Br J Haematol. 2022 Feb;196(4):1120-1123. doi: 10.1111/bjh.17902. Epub 2021 Oct 14.

Authors

Jacob R Greenmyer¹, Whitney S Thompson¹, Nicole L Hoppman², Shakila Khan³, Mrinal S Patnaik⁴, Lisa A Schimmenti⁵, Mira A Kohorst³

Affiliations

¹ Mayo Clinic, Pediatric and Adolescent Medicine, Rochester, MN, USA.
² Mayo Clinic, Laboratory Medicine and Pathology, Rochester, MN, USA.
³ Mayo Clinic, Pediatric Hematology and Oncology, Rochester, MN, USA.
⁴ Mayo Clinic, Hematology and Internal Medicine, Rochester, MN, USA.
⁵ Mayo Clinic, Clinical Genomics, Rochester, MN, USA.

PMID: 34651298
DOI: 10.1111/bjh.17902

No abstract available

Keywords: 3q21; GATA2; cytogenetics; emberger; myelodysplastic syndrome.

Publication types

Case Reports
Letter

MeSH terms

Child
Chromosome Deletion
Chromosomes, Human, Pair 3 / immunology
Female
GATA2 Transcription Factor / immunology*
Humans
Male
Myelodysplastic Syndromes / immunology*

Substances

GATA2 Transcription Factor
GATA2 protein, human

Supplementary concepts

Chromosome 3, monosomy 3q21 23