Effect of pH on Fluorescence Spectra of Coumarin Derivatives

J Fluoresc. 2022 Jan;32(1):57-66. doi: 10.1007/s10895-021-02829-7. Epub 2021 Oct 14.

Abstract

Colourless crystalline solid coumarin with a bitter taste and sweet vanilla-like odor mostly acts as chemical protection against predators in plants. Anticoagulants (blood thinners), anti-fungicidal, anti-tumor and anti-inflammatory properties of coumarin are all used to treat skin diseases. Because of internal charge transfer (ICT), coumarin molecules displayed a solvatochromic effect in various solvents of varying polarity. The emission wavelength dependent fluorescence intensity was also affected by pH.

Keywords: Anticoagulants; Fluorescence; Internal charge transfer (ICT) and pH effect; Solvatochromic effect.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents
  • Anticoagulants
  • Antifungal Agents
  • Antineoplastic Agents
  • Coumarins / chemistry*
  • Coumarins / pharmacology
  • Drug Stability
  • Energy Transfer
  • Fluorescence*
  • Hydrogen-Ion Concentration
  • Photochemical Processes
  • Solvents
  • Spectrometry, Fluorescence*

Substances

  • Anti-Inflammatory Agents
  • Anticoagulants
  • Antifungal Agents
  • Antineoplastic Agents
  • Coumarins
  • Solvents