Direct and indirect anti-leukemic properties of activity-on-target interferons for the treatment of T-cell acute lymphoblastic leukemia

Steven Goossens; Anje Cauwels; Tim Pieters; Renate De Smedt; Sara T'Sas; André Almeida; Willem Daneels; Pieter Van Vlierberghe; Jan Tavernier

doi:10.3324/haematol.2021.278913

Direct and indirect anti-leukemic properties of activity-on-target interferons for the treatment of T-cell acute lymphoblastic leukemia

Haematologica. 2022 Jun 1;107(6):1448-1453. doi: 10.3324/haematol.2021.278913.

Authors

Steven Goossens¹, Anje Cauwels², Tim Pieters³, Renate De Smedt³, Sara T'Sas³, André Almeida³, Willem Daneels⁴, Pieter Van Vlierberghe⁵, Jan Tavernier²

Affiliations

¹ Cancer Research Institute Ghent (CRIG), Ghent University, B-9000 Ghent, Belgium; Department of Diagnostic Sciences, Ghent University, B-9000 Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, B-9000 Ghent.
² Cancer Research Institute Ghent (CRIG), Ghent University, B-9000 Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, B-9000 Ghent, Belgium; VIB-UGent Center for Medical Biotechnology, B-9000 Ghent, Belgium; Orionis Biosciences BV, B-9052 Ghent.
³ Cancer Research Institute Ghent (CRIG), Ghent University, B-9000 Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, B-9000 Ghent.
⁴ Cancer Research Institute Ghent (CRIG), Ghent University, B-9000 Ghent, Belgium; Department of Hematology, Ghent University Hospital, B-9000 Ghent.
⁵ Cancer Research Institute Ghent (CRIG), Ghent University, B-9000 Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, B-9000 Ghent. pieter.vanvlierberghe@ugent.be.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Humans
Interferons*
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma* / drug therapy
T-Lymphocytes

Substances

Interferons

Grants and funding

Funding: This work was supported by the Stichting ME TO YOU, the Ghent University Research Fund (BOF-UGent) and the Research Foundation Flanders (FWO).