Roux-en-Y Gastric Bypass Vs Sleeve Gastrectomy in Super Obesity: a Systematic Review and Meta-Analysis

Obes Surg. 2022 Jan;32(1):170-185. doi: 10.1007/s11695-021-05745-8. Epub 2021 Oct 12.

Abstract

Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are safe procedures that may present sub-optimal results in superobesity (SO). A meta-analysis was performed aiming to summarize the available evidence on weight loss (primary outcome) and comorbidities resolution of LRYGB and LSG in patients with SO (BMI ≥ 50 kg/m2). From the 16 included studies, 7 integrated the meta-analysis. LRYGB showed a significantly higher weight loss at 6 to 12-months, but not after 24 months and a higher dyslipidemia resolution at 12 months. When compared with LSG, LRYGB achieved better weight loss after 6 and 12 months and higher dyslipidemia resolution after 1 year. There were no significant differences for resolution of the other co-morbidities studied.

Keywords: Bariatric surgery; Comorbidity resolution; LRYGB; LSG; Laparoscopic Roux-en-Y gastric bypass; Laparoscopic sleeve gastrectomy; Meta-analysis; Super obesity; Weight loss.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Gastrectomy / methods
  • Gastric Bypass* / methods
  • Humans
  • Laparoscopy* / methods
  • Obesity / surgery
  • Obesity, Morbid* / surgery
  • Treatment Outcome
  • Weight Loss