Neurobiology: Novel peptide pathways impact threat discrimination

Claire E Stelly; Jonathan P Fadok

doi:10.1016/j.cub.2021.08.053

Neurobiology: Novel peptide pathways impact threat discrimination

Curr Biol. 2021 Oct 11;31(19):R1117-R1119. doi: 10.1016/j.cub.2021.08.053.

Authors

Claire E Stelly¹, Jonathan P Fadok²

Affiliations

¹ Department of Psychology and Brain Institute, Tulane University, New Orleans, LA 70118, USA.
² Department of Psychology and Brain Institute, Tulane University, New Orleans, LA 70118, USA. Electronic address: jfadok@tulane.edu.

Abstract

Discriminating dangerous predictive stimuli from non-threatening stimuli is vital for maintaining optimal behavioral strategies. A new study finds that novel stress-related peptide pathways to the dopaminergic midbrain play a fundamental role in threat generalization.

Publication types

Comment

MeSH terms

Fear*
Generalization, Psychological
Neurobiology*
Peptides

Substances

Peptides

Grants and funding

R01 MH122561/MH/NIMH NIH HHS/United States