Significantly reduced abilities to cross-neutralize SARS-CoV-2 variants by sera from convalescent COVID-19 patients infected by Delta or early strains

Cell Mol Immunol. 2021 Nov;18(11):2560-2562. doi: 10.1038/s41423-021-00776-8. Epub 2021 Oct 11.

Ting Pan^#^{1

2}, Zhongwei Hu^#³, Fengyu Hu^#³, Yiwen Zhang^#¹, Bingfeng Liu¹, Changwen Ke⁴, Qiumin She³, Xin He⁵, Xiaoping Tang^{6

7}, Hui Zhang^{8

9}

¹ Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China.
² Center for Infection and Immunity Study, School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, China.
³ Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
⁴ Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, Guangdong, China.
⁵ Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China. hexin59@mail.sysu.edu.cn.
⁶ Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China. tangxp@gzhmu.edu.cn.
⁷ National Guangzhou Laboratory, Bio-Island, Guangzhou, Guangdong, China. tangxp@gzhmu.edu.cn.
⁸ Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China. zhangh92@mail.sysu.edu.cn.
⁹ National Guangzhou Laboratory, Bio-Island, Guangzhou, Guangdong, China. zhangh92@mail.sysu.edu.cn.

^# Contributed equally.

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