Recent Progress in the Synthesis of Heterocycles based on 1,3-diketones

Abstract

N,O-heterocycles containing the dicarbonyl ring play a significant role in heterocyclic and therapeutic chemistry. Since the discovery of 1,3-diketones, numerous research works have been achieved regarding the synthesis and its chemical reactivity. In this review, we have described the most relevant publications involving β-diketone compounds published during the period between 2018 to date. In addition, we include the 1,3-diketones-based heterocyclic compounds prepared by various synthetic methodologies.

Keywords: 1; 3-diketones; dynthesis; heterocyclic compounds; multi-compound reaction; teactivity; therapeutic chemistry.