Utility Values in Colorectal Cancer Patients Treated with Chemotherapy

Cancer Invest. 2022 Jan;40(1):46-54. doi: 10.1080/07357907.2021.1992632. Epub 2021 Oct 26.

Abstract

Calculating utility values in colorectal cancer (CRC) patients under chemotherapy treatment is important for studies of economic evaluations. The EQ-5D-5L and composite time trade-off (cTTO) were used to calculate utility values in 105 patients with CRC in Iran. The mean EQ-5D-5L index and cTTO values were 0.45 ± 0.03 and 0.51 ± 0.02, respectively. Anxiety and pain were the most common problems reported by the patients. The BetaMix showed that lower mean utility values were significantly associated with females, aging, a low level of income, a greater number of comorbidities, and an advanced stage of cancer.

Keywords: Colorectal; EQ-5D-5L; cTTO; utility.

MeSH terms

  • Aged
  • Colorectal Neoplasms / drug therapy*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Quality of Life
  • Surveys and Questionnaires / standards*