Novel technique for recanalization of severe hepaticojejunal obstruction using a transseptal needle in a pediatric liver transplant recipient

Pediatr Transplant. 2022 Mar;26(2):e14160. doi: 10.1111/petr.14160. Epub 2021 Oct 11.

Abstract

Background: Endoscopic and PTB interventions are common nonsurgical interventions for biliary anastomotic strictures that occur after liver transplantation. When these nonsurgical interventions fail, surgical re-anastomosis is considered; however, this is quite invasive and can cause additional injury that may lead to graft loss. We report a case in which conventional nonsurgical interventions failed, but a new method that involve the use of a transseptal needle-a device to create a transseptal left-heart access during cardiac catheter interventions-was successfully used in recanalization of the hepaticojejunal anastomotic obstruction.

Case: A 21-year-old man, who had received living-donor liver transplantation for biliary atresia at the age of 23 months presented with recurrent cholangitis and liver dysfunction due to a biliary anastomotic stricture of the hepaticojejunostomy. Therapeutic interventions for biliary stricture, including the PTB approach, double-balloon enteroscopic approach, and rendezvous approach failed. We then performed needle puncture of the anastomotic obstruction using a transseptal needle and succeeded in recanalizing the complete anastomotic obstruction. To perform the procedures safely, we evaluated the organ and needle positions using biplane fluoroscopy and placed a balloon in the afferent jejunal limb as a target for puncture. The 12 Fr catheter via the biliary route was removed 7 months after the procedure, without using a catheter, there was no recurrent stricture or cholangitis for 26 months.

Conclusion: Using a transseptal needle to manage hepaticojejunal anastomotic obstruction can reduce the number of patients who need surgical re-anastomosis.

Keywords: biliary complications; biliary obstruction; biliary stricture; interventional radiology; living-donor liver transplantation; transseptal needle.

Publication types

  • Case Reports

MeSH terms

  • Anastomosis, Surgical
  • Biliary Atresia / surgery
  • Cholangiography
  • Cholestasis / diagnostic imaging
  • Cholestasis / therapy*
  • Constriction, Pathologic / diagnostic imaging
  • Constriction, Pathologic / therapy
  • Fluoroscopy
  • Humans
  • Jejunostomy / methods*
  • Liver Transplantation*
  • Male
  • Needles*
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / therapy*
  • Punctures
  • Radiography, Interventional
  • Tomography, X-Ray Computed
  • Young Adult