[Surgical de-escalation in gynecologic oncology]

Bull Cancer. 2021 Dec;108(12):1155-1161. doi: 10.1016/j.bulcan.2021.06.012. Epub 2021 Oct 7.
[Article in French]

Abstract

The evolution of knowledge in gynecologic oncology is leading to surgical de-escalation in several areas, particularly in lymph node staging. Sentinel lymph node biopsy that was initially used in low and intermediate risk endometrial cancer, has now been extended to high-intermediate and high-risk endometrial cancer. Sentinel lymph node biopsy plays also an important role in the nodal staging of early-stage cervical cancer. The radicality of hysterectomies in patients with early cervical cancer is under debate. Similarly, surgical staging with para-aortic lymphadenectomy in locally advanced cervical cancer should be performed only for few cases. Systematic pelvic and para-aortic lymphadenectomy in patients with advanced ovarian cancers is not recommended anymore.

Keywords: Cancers gynécologiques; Désescalade chirurgicale; Ganglion sentinelle; Gynecological cancers; Lymphadenectomy; Lymphadénectomie; Sentinel lymph node; Surgical de-escalation.

Publication types

  • Review

MeSH terms

  • Chemoradiotherapy / methods
  • Conservative Treatment / methods
  • Endometrial Neoplasms / pathology
  • Endometrial Neoplasms / surgery*
  • Female
  • Fertility Preservation / methods
  • Humans
  • Hysterectomy / trends
  • Lymph Node Excision / trends
  • Neoplasm Staging
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / surgery*
  • Pelvis
  • Sentinel Lymph Node Biopsy / trends
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / surgery*