[SAPHO syndrome with chronic tonsillitis: a case report and literature review]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Oct;35(10):944-947. doi: 10.13201/j.issn.2096-7993.2021.10.018.
[Article in Chinese]

Abstract

SAPHO syndrome is a rare disease which affects the bones, joints, and skin. It is often misdiagnosed and treated mistakenly because of various clinical manifestations and general lack of awareness about the disease. The pathogenesis is inadequately understood, as a result, current therapy is empirical and aimed to control inflammatory process and alleviate pain. This paper summarizes the clinical manifestations and diagnosis and treatment scheme of SAPHO syndrome, and presents a case of patient with SAPHO syndrome who was treated in our department for bilateral tonsillectomy due to repeated pharyngalgia and fever for 10 years. Interestingly, the patient is getting better after the operation. The case is reported so as to provide reference for the diagnosis and treatment of SAPHO syndrome.

Keywords: SAPHO syndrome; hyperotosis; pustulosis; tonsillitis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acquired Hyperostosis Syndrome* / diagnosis
  • Chronic Disease
  • Humans
  • Pain
  • Skin
  • Tonsillitis* / diagnosis

Grants and funding

国家自然科学基金面上项目(No: 81570926)