Comment on "Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c.Abcb4-/- mouse model of PFIC3"

J Hepatol. 2022 Mar;76(3):749-751. doi: 10.1016/j.jhep.2021.09.033. Epub 2021 Oct 6.
No abstract available

Keywords: Bile; Child; Cholestasis; Dependovirus; Genetic therapy; Liver Cirrhosis; Phospholipids; progressive familial intrahepatic 3.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Animals
  • Cholestasis, Intrahepatic* / genetics
  • Humans
  • Mice
  • Phenotype
  • RNA, Messenger / genetics

Substances

  • RNA, Messenger