Molecular surveillance of malaria scales up

Philipp Schwabl; Daniel E Neafsey

doi:10.1016/j.pt.2021.09.010

Molecular surveillance of malaria scales up

Trends Parasitol. 2021 Dec;37(12):1020-1021. doi: 10.1016/j.pt.2021.09.010. Epub 2021 Oct 5.

Authors

Philipp Schwabl¹, Daniel E Neafsey²

Affiliations

¹ Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
² Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: neafsey@hsph.harvard.edu.

PMID: 34625343
DOI: 10.1016/j.pt.2021.09.010

Abstract

Parasite and vector genetic data can guide malaria control, and technological advances are enabling more informative genetic data generation at unprecedented scales. Jacob et al. employ multiplexed amplicon sequencing to profile parasite genetic diversity from thousands of malaria samples, illuminating spatiotemporal patterns of drug resistance to inform regional drug policy change.

Keywords: amplicon sequencing; epidemiology; genome; genotyping; malaria.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Drug Resistance / genetics
Humans
Malaria* / epidemiology
Malaria* / parasitology
Malaria, Falciparum* / parasitology
Plasmodium falciparum / genetics