Diagnostic Impact of Clinical Manifestations of Group A Streptococcal Pharyngitis

Infect Chemother. 2021 Sep;53(3):553-556. doi: 10.3947/ic.2021.0042.

Abstract

This study aims to identify the clinical characteristics for diagnosing streptococcal pharyngitis. The correlation between eighteen clinical manifestations and rapid antigen detection test results was analyzed. Among 205 patients, five clinical manifestations, pharyngeal hemorrhage (odds ratio [OR] = 11.85), palatal hemorrhage (OR = 9.32), tonsillar swelling (OR = 4.37), rash (OR = 3.02), and enlarged cervical nodes (OR = 1.91), were significantly correlated with group A Streptococcus (GAS) pharyngitis. Traditional indicators such as fever, pharyngeal redness, acute onset, headache, rhinorrhea, cough, tonsillar exudate, and cervical tenderness were not statistically related to GAS pharyngitis. Therefore, physicians should be cautious in using these traditional indicators.

Keywords: Diagnosis; Group A streptococcus; Pharyngitis; Rapid test; Streptococcus pyogenes.