[Non-coding RNAs in viral myocarditis]

Sheng Wu Gong Cheng Xue Bao. 2021 Sep 25;37(9):3101-3107. doi: 10.13345/j.cjb.200698.
[Article in Chinese]

Abstract

Viral myocarditis (VMC) is a disease characterized by inflammation of myocardial cells caused by viral infection. Since the pathogenesis mechanism of VMC has not been fully elucidated, the diagnosis and treatment of this disease remains extremely challenging. Non-coding RNAs (ncRNAs) are a class of RNAs that do not encode proteins. An increasing number of studies have shown that ncRNAs are involved in regulating the occurrence and development of VMC, thus providing potential new targets for the treatment and diagnosis of VMC. This review summarizes the possible roles of ncRNAs in the pathogenesis and diagnosis of VMC revealed recently.

Keywords: coxsackievirus; non-coding RNAs; pathogenesis; therapeutic target; viral myocarditis.

Publication types

  • Review

MeSH terms

  • Coxsackievirus Infections*
  • Enterovirus B, Human
  • Humans
  • Inflammation
  • Myocarditis* / genetics
  • Virus Diseases* / diagnosis
  • Virus Diseases* / genetics