Poly(ionic liquid)-Based Efficient and Robust Antiseptic Spray

ACS Appl Mater Interfaces. 2021 Oct 20;13(41):48358-48364. doi: 10.1021/acsami.1c11481. Epub 2021 Oct 6.

Abstract

Exploring efficient and robust antibacterial materials is crucially important for human health and ecological security. Compared with intrinsically antibacterial materials, materials modified with antibacterial agents either by chemical or physical modification can simultaneously maintain basic functions and antibacterial properties. In particular, physical modification with antiseptic sprays is quite suitable for large-size objects in our daily life but restricted by high volatility of the antibacterial agents or poor adhesion strength between the antibacterial agents and the targeted objects. In this paper, we report a poly(ionic liquid) (PIL-Cn)-based efficient and robust antiseptic spray that exhibits long-term antibacterial properties against both Gram-positive and Gram-negative bacteria on diverse substrates, including glass, PE, and cotton. It is believed that this work will provide an alternative for current antiseptic sprays for usage in our daily life and hospitals.

Keywords: antibacterial; antiseptic spray; multibinding; poly(ionic liquid); synergistic effect.

MeSH terms

  • Aerosols
  • Anti-Infective Agents, Local / chemical synthesis
  • Anti-Infective Agents, Local / pharmacology*
  • Anti-Infective Agents, Local / toxicity
  • Cell Membrane / drug effects
  • Dental Pulp / cytology
  • Escherichia coli / drug effects
  • Ionic Liquids / chemical synthesis
  • Ionic Liquids / pharmacology*
  • Ionic Liquids / toxicity
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Polymers / chemical synthesis
  • Polymers / pharmacology*
  • Polymers / toxicity
  • Staphylococcus aureus / drug effects
  • Stem Cells / drug effects

Substances

  • Aerosols
  • Anti-Infective Agents, Local
  • Ionic Liquids
  • Polymers