Predicting Sarcopenia of Female Elderly from Physical Activity Performance Measurement Using Machine Learning Classifiers

Clin Interv Aging. 2021 Sep 27:16:1723-1733. doi: 10.2147/CIA.S323761. eCollection 2021.

Abstract

Purpose: Sarcopenia is a symptom in which muscle mass decreases due to decreasing in the number of muscle fibers and muscle cross-sectional area as aging. This study aimed to develop a machine learning classification model for predicting sarcopenia through a inertial measurement unit (IMU)-based physical performance measurement data of female elderly.

Patients and methods: Seventy-eight female subjects from an elderly population (aged: 78.8±5.7 years) volunteered to participate in this study. To evaluate the physical performance of the elderly, the experiment conducted timed-up-and-go test (TUG) and 6-minute walk test (6mWT) with worn a single IMU. Based on literature review, 132 features were extracted from collected data. Feature selection was performed through the Kruskal-Wallis test, and features datasets were constructed according to feature selection. Three major machine learning-based classification algorithms classified the sarcopenia group in each dataset, and the performance of classification models was compared.

Results: As a result of comparing the classification model performance for sarcopenia prediction, the k-nearest neighborhood algorithm (kNN) classification model using 40 major features of TUG and 6mWT showed the best performance at 88%.

Conclusion: This study can be used as a basic research for the development of self-monitoring technology for sarcopenia.

Keywords: inertial measurement unit; machine learning; physical activity; sarcopenia.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Exercise
  • Female
  • Humans
  • Machine Learning
  • Postural Balance
  • Sarcopenia* / diagnosis
  • Time and Motion Studies