Xenogeneic support for the recovery of human donor organs

John D O'Neill; Brandon A Guenthart; Ahmed E Hozain; Matthew Bacchetta

doi:10.1016/j.jtcvs.2021.07.055

Xenogeneic support for the recovery of human donor organs

J Thorac Cardiovasc Surg. 2022 Apr;163(4):1563-1570. doi: 10.1016/j.jtcvs.2021.07.055. Epub 2021 Sep 6.

Authors

John D O'Neill¹, Brandon A Guenthart², Ahmed E Hozain³, Matthew Bacchetta⁴

Affiliations

¹ Department of Cell Biology, State University of New York Downstate Medical Center, SUNY Downstate Health Sciences University, Brooklyn, NY.
² Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif.
³ Department of Surgery, State University of New York Downstate Medical Center, SUNY Downstate Health Sciences University, Brooklyn, NY.
⁴ Department of Thoracic Surgery, Vanderbilt University, Nashville, Tenn; Department of Cardiac Surgery, Vanderbilt University, Nashville, Tenn; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tenn. Electronic address: matthew.bacchetta@vumc.org.

PMID: 34607726
DOI: 10.1016/j.jtcvs.2021.07.055

Abstract

VIDEO ABSTRACT.

Keywords: acute lung injury; aspiration pneumonitis; bioengineering; cross-circulation; ex vivo lung perfusion; ischemia–reperfusion injury; lung; organ crosstalk; organ donation; organ recovery; perfusion; regeneration; transplantation; xenogeneic; xenotransplantation.

Publication types

Editorial
Video-Audio Media

MeSH terms

Animals
Extracorporeal Circulation*
Humans
Lung Transplantation*
Organ Preservation / methods*