A hybrid approach to forecast the COVID-19 epidemic trend

PLoS One. 2021 Oct 4;16(10):e0256971. doi: 10.1371/journal.pone.0256971. eCollection 2021.

Abstract

Studying the progress and trend of the novel coronavirus pneumonia (COVID-19) transmission mode will help effectively curb its spread. Some commonly used infectious disease prediction models are introduced. The hybrid model is proposed, which overcomes the disadvantages of the logistic model's inability to predict the number of confirmed diagnoses and the drawbacks of too many tuning parameters of the SEIR (Susceptible, Exposed, Infectious, Recovered) model. The realization and superiority of the prediction of the proposed model are proven through experiments. At the same time, the influence of different initial values of the parameters that need to be debugged on the hybrid model is further studied, and the mean error is used to quantify the prediction effect. By forecasting epidemic size and peak time and simulating the effects of public health interventions, this paper aims to clarify the transmission dynamics of COVID-19 and recommend operation suggestions to slow down the epidemic. It is suggested that the quick detection of cases, sufficient implementation of quarantine and public self-protection behaviours are critical to slow down the epidemic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19 / epidemiology
  • COVID-19 / pathology*
  • COVID-19 / transmission
  • COVID-19 / virology
  • Humans
  • Logistic Models
  • Models, Theoretical
  • Quarantine
  • SARS-CoV-2 / isolation & purification

Grants and funding

This work was supported in part by the Natural Science Foundation of China under Grant 62063004 and 61762033, and by the Hainan Provincial Natural Science Foundation of China under Grant 2019RC018, in part by the Hainan Provincial Higher Education Research Project under Grant Hnky2019-73, in part by the Key Research Project of Haikou College of Economics under Grant HJKZ18-01.