Kikuchi-Fujimoto Disease Associated With Mycoplasma Pneumoniae Infection

Rui-Bin Yu; Yi-Jia Chen; Chun-Hsiang Chang; Yen-Lin Chen; Jeng-Wen Chen

doi:10.1177/01455613211044225

Kikuchi-Fujimoto Disease Associated With Mycoplasma Pneumoniae Infection

Ear Nose Throat J. 2024 Apr;103(4):NP223-NP225. doi: 10.1177/01455613211044225. Epub 2021 Oct 2.

Authors

Rui-Bin Yu^{1

2}, Yi-Jia Chen¹, Chun-Hsiang Chang^{1

2

3}, Yen-Lin Chen^{3

4}, Jeng-Wen Chen^{1

2

3}

Affiliations

¹ Department of Otolaryngology-Head and Neck Surgery, Catholic Cardinal Tien Hospital, New Taipei City, Taiwan ROC.
² Department of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital, Taipei, Taiwan ROC.
³ School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan ROC.
⁴ Department of Pathology, Catholic Cardinal Tien Hospital, New Taipei City, Taiwan ROC.

PMID: 34605286
DOI: 10.1177/01455613211044225

Abstract

Kikuchi-Fujimoto disease (KFD) is a self-limited disease that is more common in young Asian women. Typical presentations included fever and cervical lymphadenopathy. The etiology of KFD is unknown, and diagnosis is based mainly on lymph node biopsy. KFD has been reported to be associated with Mycoplasma pneumoniae infection. However, the role of antibiotic treatment is unclear. We reported 2 cases of KFD associated with Mycoplasma pneumoniae infection and were successfully treated with a macrolide.

Keywords: Kikuchi–Fujimoto disease; macrolide; mycoplasma pneumoniae; necrotizing lymphadenitis.

MeSH terms

Biopsy
Female
Fever
Histiocytic Necrotizing Lymphadenitis* / complications
Histiocytic Necrotizing Lymphadenitis* / diagnosis
Histiocytic Necrotizing Lymphadenitis* / pathology
Humans
Lymphadenopathy*
Pneumonia, Mycoplasma* / complications
Pneumonia, Mycoplasma* / diagnosis
Pneumonia, Mycoplasma* / drug therapy