Abstract
In this study, antibacterial, antifungal, antihyaluronidase, anticollagenase and antielastase activity of Hypericum bithynicum, Malva neglecta, Morus alba, Rubus discolor, Sambucus ebulus and Smilax excelsa were investigated. Methanol extracts of M. neglecta and R. discolor and all extracts of H. bithynicum were more active against Staphylococcus epidermidis. Similarly, water extracts of M. alba and S. ebulus were more active against Streptococcus pneumonia. Additionally, S. ebulus and S. excelsa had prominent antifungal activity on Candida albicans. Besides, methanol extract of M. neglecta and n-hexane extract of H. bithynicum were determined to have significant antihyaluronidase activity. Only R. discolor showed significant antielastase effect.
MeSH terms
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Acinetobacter baumannii / drug effects
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Anti-Bacterial Agents / pharmacology*
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Antifungal Agents / pharmacology*
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Candida / drug effects*
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Candida albicans / drug effects
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Collagenases
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Enzyme Inhibitors / pharmacology*
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Escherichia coli / drug effects
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Gram-Negative Bacteria / drug effects*
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Gram-Positive Bacteria / drug effects*
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Hyaluronoglucosaminidase / antagonists & inhibitors
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Hypericum
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Klebsiella pneumoniae / drug effects
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Malva
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Matrix Metalloproteinase Inhibitors / pharmacology
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Morus
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Pancreatic Elastase / antagonists & inhibitors
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Plant Extracts / pharmacology*
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Pseudomonas aeruginosa / drug effects
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Rubus
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Sambucus
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Smilax
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Staphylococcus aureus / drug effects
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Staphylococcus epidermidis / drug effects
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Streptococcus pneumoniae / drug effects
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Streptococcus pyogenes / drug effects
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Turkey
Substances
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Anti-Bacterial Agents
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Antifungal Agents
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Enzyme Inhibitors
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Matrix Metalloproteinase Inhibitors
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Plant Extracts
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Hyaluronoglucosaminidase
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Pancreatic Elastase
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Collagenases