Serum Potassium and Mortality in High-Risk Patients: SPRINT

Hypertension. 2021 Nov;78(5):1586-1594. doi: 10.1161/HYPERTENSIONAHA.121.17736. Epub 2021 Oct 4.

Christina Byrne^#¹, Manan Pareek^#^{2

3

4}, Muthiah Vaduganathan², Tor Biering-Sørensen^{2

5

6}, Maria Lukács Krogager⁷, Kristian Hay Kragholm⁷, Kamilla Steensig⁷, Martin Bødtker Mortensen⁸, Shiva Raj Mishra⁹, Megan J McCullough¹⁰, Nihar R Desai³, Christian Torp-Pedersen^{4

7}, Michael Hecht Olsen^{11

12}, Deepak L Bhatt²

¹ Department of Cardiology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark (C.B.).
² Brigham and Women's Hospital, Heart & Vascular Center (M.P., M.V., T.B.-S., D.L.B.), Harvard Medical School, Boston, MA.
³ Department of Cardiology, Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (M.P., N.R.D.).
⁴ Department of Cardiology and Clinical Epidemiology, North Zealand Hospital, Hillerød, Denmark (M.P., C.T.-P.).
⁵ Department of Cardiology, Herlev and Gentofte Hospital, Copenhagen, Denmark (T.B.-S.).
⁶ Institute of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (T.B.-S.).
⁷ Department of Cardiology, Aalborg University Hospital, Denmark (M.L.K., K.H.K., K.S., C.T.-P.).
⁸ Department of Cardiology, Aarhus University Hospital, Denmark (M.B.M.).
⁹ World Heart Federation, Salim Yusuf Emerging Leaders Program, Geneva, Switzerland (S.R.M.).
¹⁰ Massachusetts General Hospital Corrigan Minehan Heart Center (M.J.M.S), Harvard Medical School, Boston, MA.
¹¹ Department of Internal Medicine, Holbaek Hospital, Denmark (M.H.O.).
¹² Department of Regional Health Research, University of Southern Denmark (M.H.O.).

^# Contributed equally.

Abstract

[Figure: see text].

Trial registration: ClinicalTrials.gov NCT01206062.

Keywords: antihypertensive agents; blood pressure; hypertension; mortality; potassium.