Deletion of the 3'RR cis-enhancer IgH element affects DNA repair junctions during B-cell class switch recombination

Immunol Lett. 2021 Dec:240:12-14. doi: 10.1016/j.imlet.2021.09.010. Epub 2021 Sep 29.

Authors

Melissa Ferrad¹, Nour Ghazzaui¹, Hussein Issaoui¹, Tiffany Marchiol¹, Jeanne Cook-Moreau¹, Yves Denizot²

Affiliations

¹ UMR CNRS 7276, INSERM U1262, Equipe Labellisée LIGUE 2018, Université de Limoges, CBRS, rue Pr. Descottes, 87025 Limoges, France.
² UMR CNRS 7276, INSERM U1262, Equipe Labellisée LIGUE 2018, Université de Limoges, CBRS, rue Pr. Descottes, 87025 Limoges, France. Electronic address: yves.denizot@unilim.fr.

PMID: 34599945
DOI: 10.1016/j.imlet.2021.09.010

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
B-Lymphocytes*
DNA Repair*
Enhancer Elements, Genetic*
Immunoglobulin Class Switching*
Immunoglobulin Heavy Chains / genetics*
Mice
Mice, Knockout

Substances

Immunoglobulin Heavy Chains