Cyphellophora laciniata: A new etiological agent of chromoblastomycosis

J Mycol Med. 2022 Mar;32(1):101204. doi: 10.1016/j.mycmed.2021.101204. Epub 2021 Sep 9.

Abstract

Chromoblastomycosis is a chronic subcutaneous mycosis caused by traumatic inoculation of dematiaceous fungi especially in tropical and subtropical areas. Cyphellophora genus include melanized fungi reported as etiological agents of skin and nail infections. We report a 60-year-old male from the south of Mexico with a 40-year history of chromoblastomycosis caused by Cyphellophora laciniata. The isolated fungus was identified by sequencing of the internal transcribed spacer region of rDNA. The patient was treated with itraconazole and cryosurgery with unsatisfactory results.

Keywords: Chromoblastomycosis; Cyphellophora laciniata; Itraconazole; Subcutaneous mycosis.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Ascomycota* / genetics
  • Chromoblastomycosis* / diagnosis
  • Chromoblastomycosis* / drug therapy
  • Chromoblastomycosis* / microbiology
  • Humans
  • Itraconazole / therapeutic use
  • Male
  • Middle Aged

Substances

  • Antifungal Agents
  • Itraconazole

Supplementary concepts

  • Cyphellophora laciniata