B cells and cancer

Cancer Cell. 2021 Oct 11;39(10):1293-1296. doi: 10.1016/j.ccell.2021.09.007. Epub 2021 Sep 30.

Abstract

Tumor-infiltrating B cells complement T cell-mediated antitumor immunity. A panel of experts share their views on the complexity of B cells within the tumor microenvironment, the variety of mechanisms by which these cells control tumor growth, their organization in tertiary lymphoid structures, and their association with immunotherapy response.

Publication types

  • Review

MeSH terms

  • B-Lymphocytes / metabolism*
  • Humans
  • Lymphocytes, Tumor-Infiltrating / metabolism*
  • Neoplasms / blood*