Fuzzy rough set (FRS) theory is generally used to measure the uncertainty of data. However, this theory cannot work well when the class density of a data distribution differs greatly. In this work, a relative distance measure is first proposed to fit the mentioned data distribution. Based on the measure, a relative FRS model is introduced to remedy the mentioned imperfection of classical FRSs. Then, the positive region, negative region, and boundary region are defined to measure the uncertainty of data with the relative FRSs. Besides, a relative fuzzy dependency is defined to evaluate the importance of features to decision. With the proposed feature evaluation, we propose a feature selection algorithm and design a classifier based on the maximal positive region. The classification principle is that an unlabeled sample will be classified into the class corresponding to the maximal degree of the positive region. Experimental results show the relative fuzzy dependency is an effective and efficient measure for evaluating features, and the proposed feature selection algorithm presents better performance than some classical algorithms. Besides, it also shows the proposed classifier can achieve slightly better performance than the KNN classifier, which demonstrates that the maximal positive region-based classifier is effective and feasible.