Artifactual prolongation of the activated partial thromboplastin time by amikacin or gentamicin with ellagic acid, but not silica activated reagent

Int J Lab Hematol. 2022 Apr;44(2):e72-e75. doi: 10.1111/ijlh.13718. Epub 2021 Sep 29.

¹ Department of Internal Medicine, Anan Medical Center, Tokushima, Japan.
² Department of Medical Technology, Tokushima University Hospital, Tokushima, Japan.
³ Department of Pharmacy, Tokushima University Hospital, Tokushima, Japan.
⁴ Department of Medical Technology, Anan Medical Center, Tokushima, Japan.
⁵ Department of Community Medicine and Medical Science, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
⁶ Department of Hematology, Endocrinology and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

No abstract available

Keywords: activated partial thromboplastin time; amikacin; aminoglycosides; ellagic acid; gentamicin; silica.

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