Atherosclerosis, Ischemia, and Anticancer Drugs

Heart Views. 2021 Apr-Jun;22(2):127-133. doi: 10.4103/HEARTVIEWS.HEARTVIEWS_45_20. Epub 2021 Aug 19.

Abstract

The heart is affected by cardiotoxicity of anticancer drugs. Myocardium, pericardium and endocardium can be affected. Besides these coronary arteries can be affected by accelerated atherosclerosis. Various pathogenic mechanisms have been proposed that underlie the ischemic complications of anticancer drugs. In this review we discuss the atherosclerotic and ischemic complications of anticancer drugs.

Keywords: Accelerated atherosclerosis; anticancer drugs; cardio-oncology; coronary artery disease; myocardial infarction.

Publication types

  • Review