Evaluation of Residual Monomers Eluted from Pediatric Dental Restorative Materials

Biomed Res Int. 2021 Sep 16:2021:6316171. doi: 10.1155/2021/6316171. eCollection 2021.

Abstract

Unreacted monomers eluted from resin-based restorative materials have been considered a reason of local and systemic adverse reactions. This study was designed to determine the effect of finishing and polishing procedures on the elution of Bis-GMA, TEGDMA, UDMA, and HEMA monomers from compomer and bulk-fill composite resins. Bulk-fill composite (3M ESPE GmbH, Seefeld, Germany) and compomer (Dentsply DeTrey GmbH, Konstanz, Germany) specimens with 3 × 4 mm diameters were prepared. The specimens were randomly divided into two groups, and finishing-polishing procedures were applied only to the experimental groups. Release of residual monomers was analyzed by using High-Performance Liquid Chromatography (HPLC) after 24, 48, and 72 hours. Repeated measures ANOVA and Tukey post hoc tests were used for comparisons. Finishing and polishing procedures had a significant effect on reducing the quantity of UDMA release in the Filtek™ Bulk Fill composite and Bis-GMA, HEMA, and TEGDMA in the Dyract XP compomer (p < 0.05). The restorative materials investigated here are not chemically stable after polymerization, and concentrations of eluted monomers may reach critical toxicity levels even after one restoration placement. Finishing and polishing procedures are mandatory to reduce residual monomers.

MeSH terms

  • Bisphenol A-Glycidyl Methacrylate / analysis
  • Calibration
  • Child
  • Dental Materials / chemistry*
  • Humans
  • Limit of Detection
  • Methacrylates / analysis
  • Polyethylene Glycols / analysis
  • Polymethacrylic Acids / analysis
  • Polyurethanes / analysis
  • Regression Analysis
  • Resins, Synthetic / analysis*

Substances

  • Dental Materials
  • Methacrylates
  • Polymethacrylic Acids
  • Polyurethanes
  • Resins, Synthetic
  • urethane dimethacrylate luting resin
  • triethylene glycol dimethacrylate
  • Polyethylene Glycols
  • Bisphenol A-Glycidyl Methacrylate
  • hydroxyethyl methacrylate