Molecular allergology approach to allergic asthma

Ioana Agache; Elizabeth Palmer; Didem Sanver; Max Kirtland; Mohamed H Shamji

doi:10.1016/j.mam.2021.101027

Molecular allergology approach to allergic asthma

Mol Aspects Med. 2022 Jun:85:101027. doi: 10.1016/j.mam.2021.101027. Epub 2021 Sep 25.

Authors

Ioana Agache¹, Elizabeth Palmer², Didem Sanver³, Max Kirtland², Mohamed H Shamji²

Affiliations

¹ Faculty of Medicine, Transylvania University, Brasov, Romania. Electronic address: ibrumaru@unitbv.ro.
² Imperial College, Faculty of Medicine, National Heart & Lung Institute, London, UK.
³ Imperial College, Faculty of Medicine, National Heart & Lung Institute, London, UK; Necmettin Erbakan University, Engineering & Architecture Faculty, Department of Food Engineering, Konya, Turkey.

PMID: 34579961
DOI: 10.1016/j.mam.2021.101027

Abstract

Allergic asthma is a frequently encountered and well described asthma phenotype. However, its precise mechanisms are less known. The tools for targeted selection of patients for an optimal response to intervention (prevention or treatment) are also lacking. Here we explore the potential of the molecular allergology approach to achieve a better understanding of allergic asthma mechanisms, a precise diagnosis and an optimal management of these patients.

Keywords: 6): allergens; Asthma; Component resolved diagnosis; Endotypes; Immunotherapy; Single cell analysis.

Publication types

Review

MeSH terms

Allergens*
Asthma* / diagnosis
Asthma* / genetics
Asthma* / therapy
Humans
Phenotype

Substances

Allergens