We have investigated the influence of electric dipole moment in different periodic two-dimensional network on the electronic structure properties of graphene. Although the control of doping level in graphene within a van der Waals heterostructure constitutes a difficult task, the dipolar nature of the different molecular stacks can be used to control its electrostatic properties. First, we demonstrate that the orientation and magnitude of the adsorbed molecular dipole moments allow to control the electrical behaviour of graphene, and acts as an electrostatic gate that shifts neutrality point of graphene to behave as n- or p-doped materials. Then, we show that the presence of local dipole moment in SAN induces an electrostatic potential in graphene that creates well-defined patterned regions with different electronic characteristics that would influence the confinement of molecular species.